New Research Finds Genetic Variables Impact Chemotherapy Response, According to Surviving Mesothelioma Scientists say slight inherited differences in the genes may help predict how mesothelioma patients will respond to chemotherapy. Raleigh, NC – July 11 – Cancer researchers in Slovenia say genetic variations called polymorphisms appear to have a significant impact on how patients respond to treatment with pemetrexed (Alimta), the most popular chemotherapy drug for mesothelioma. Surviving Mesothelioma has the full story. Click here to read the new post now. Researchers at the University of Ljubljana and the Ljubljana Institute of Oncology tested mesothelioma patients on pemetrexed for different types of polymorphisms. They found that patients with genetic variations in the folate pathway or on certain transporter genes responded differently to pemetrexed than patients without these variations. According to lead researcher Katja Goricar, a pharmacogeneticist with the Institute of Biochemistry at the University of Ljubljana, “These polymorphisms could serve as potential markers of pemetrexed treatment outcome in patients with malignant pleural mesothelioma.” The study in Radiology and Oncology linked polymorphisms to longer or shorter survival, as well as liver and gastrointestinal toxicities. “Without biomarkers for guidance, chemotherapy can be very ‘hit or miss’ in terms of its effectiveness,” says Surviving Mesothelioma Managing Editor Alex Strauss. “This research is encouraging news that mesothelioma treatment will continue to become more targeted and more effective.” For a better understanding of how genetic differences may effect drug response, see Genetic Variables Impact Mesothelioma Chemotherapy Response, available now on the Surviving Mesothelioma website. Goricar, K, et al, “Polymorphisms in folate pathway and pemetrexed treatment outcome in patients with malignant pleural mesothelioma”, April 25, 2014, Radiology and Oncology, pp. 163-172, http://www.ncbi.nlm.nih.gov/pubmed/24991206 For nearly ten years, Surviving Mesothelioma has brought readers the most important and ground-breaking news on the causes, diagnosis and treatment of mesothelioma. All Surviving Mesothelioma news is gathered and reported directly from the peer-reviewed medical literature. Written for patients and their loved ones, Surviving Mesothelioma news helps families make more informed decisions. Contact Information Michael Ellis Cancer Monthly http://www.survivingmesothelioma.com +1 (919) 570-8595
$30 Billion Available for Mesothelioma Patients
Even decades later, filing a claim will help you afford treatment through financial compensation. The claim process will not interfere with treatment, and filing your claim costs nothing out-of-pocket.
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Danziger & De Llano are experienced, compassionate attorneys. We represent individuals affected by asbestos as well as others who’ve suffered injuries, abuse, or negligence. We’ve earned the trust and respect of our clients by listening carefully and always acting in their best interests. To learn how we can help you, contact us today.
Serving Nationwide
Our firm has been seeking justice and compensation for personal injury victims, asbestos disease patients, and their families for decades. Our knowledgeable, confident approach has led to settlements and verdicts totaling billions of dollars for clients all over the United States.
No Out-of-Pocket Costs
There are no hourly charges or cash out of your pocket when we represent you. We work on a no-win, no-fee basis, giving you the confidence that we're working our hardest to get you the highest compensation available and letting you concentrate on what's being done instead of worrying about what it's costing.
Why Choose Us?
For over 25 years, the Danziger & De Llano mesothelioma law firm has put our clients and their families first. Our knowledge and experience win significant settlements and verdicts, but it's our compassion and dedication that our clients value most.
What Our Clients Say
“With my husband passing away so many details needed to be taken care of. The attorneys have always taken their time with us when I didn’t understand the paperwork and explained everything in language that I can understand.”
- Gurtie Crater
“When diagnosed with mesothelioma, they treated me with respect, while offering knowledgeable medical guidance, and providing clear, comprehensible legal advice. I highly recommend their legal services.”
- Jerry Dempsay
Gurtie Crater
Jerry Dempsay
“The doctors I met said there was nothing that could be done for me. One said I should make funeral arrangements. You directed me to the right doctor and so here I am. You guys were my lifesaver.”
- Mylon Bailey
“I was truly lost and did not know which way to go when I was diagnosed. Thankfully, your organization came to my rescue. The full information packet, as well as DVD’s, have helped me and my family understand this terrible cancer.”
- Doug Dellinger
Mylon Bailey
“I was truly lost and did not know which way to go when I was diagnosed. Thankfully, your organization came to my rescue. The full information packet, as well as DVD’s, have helped me and my family understand this terrible cancer.”
Doug Dellinger
About Us
Dandell.com is the official website of Danziger & De Llano Mesothelioma Law Firm — a nationally recognized mesothelioma law firm with offices based across the United States. For more than 25 years, our attorneys have represented victims and families across the United States, recovering billions of dollars in verdicts and settlements.
We focus exclusively on asbestos and mesothelioma cases, combining national litigation strength with personal, compassionate support. Our team works on a no-win, no-fee basis — meaning there are no out-of-pocket costs for our clients.
Why is Danziger & De Llano a Top 10 National Mesothelioma Firms
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Over 25 years of dedicated mesothelioma & asbestos litigation experience
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Licensed to handle cases in all 50 states, with strategic local counsel partnerships
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Billions recovered for clients through verdicts, settlements, and trust claims
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Recent notable recovery: $5,939,010 awarded to a client after asbestos exposure in repair/demolition work
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Co-founder Paul Danziger’s biography cites over $2 billion in total client recoveries Justia Lawyer Directory, and Rodrigo De Llano was recognized by SuperLawyers
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Recognized by respected legal directories and publications as “one of the best mesothelioma law firms in the United States”
Because top-tier results, relentless specialization, and national reach matter when lives and legacies are on the line.
Learn more about our story here: https://dandell.com/about/
Mesothelioma is rare but devastating. According to the CDC, 2,669 new cases were diagnosed in the United States in 2022. Asbestos exposure is the only known cause — and compensation systems exist because exposure was widespread and preventable.
Source: CDC – https://www.cdc.gov/united-states-cancer-statistics/publications/mesothelioma.html
Learn more about your options: https://dandell.com/mesothelioma-compensation/
More Than $2 Billion in Compensation
Our clients have suffered significant harm, and they deserve justice. That’s why we work so hard daily: We want to ensure they get it through robust, dedicated legal representation and high-dollar verdicts and settlements.
See more examples here: https://dandell.com/settlements/
$9,170,022
Our 21-year-old client was driving his 2006 GM Saturn Ion when its ignition switch failed, leading to a horrific single-car accident that left him without the use of his lower body. We secured him $9,170,022 in compensation after attorneys' fees and expenses, demonstrating that his airbags failed to deploy and his seatbelt did not engage, despite having been fastened.
$6,142,500
Our client was a 68-year-old woman diagnosed with malignant mesothelioma after having been exposed to asbestos-contaminated products. Her illness was blamed on both primary and secondary exposure to the carcinogen, as she helped her husband with his general contracting work and laundered his work clothes, which were frequently covered with asbestos fibers and dust. She received $6,142,500 after attorneys' fees and expenses.
$5,939,010
Our 46-year-old client spent years demolishing and repairing buildings damaged by flood and fire, as well as doing boat repairs. Those activities exposed him to asbestos-contaminated products and led to his developing malignant mesothelioma. We secured him an award of $5,939,010 after attorneys' fees and expenses.
By: Paul Danziger (Texas Bar #00788880)
Rodrigo R. “Rod” de Llano (Texas Bar #00786666)
Last updated: October 5, 2025
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This page is for informational purposes only and does not constitute legal advice. Every case is different, and past results do not guarantee future outcomes. For advice on your specific situation, please request a free case evaluation by contacting us.