Mesothelioma Gives Stem Cells A Bad Name

Verastem Announces Initiation of COMMAND Study in Japan Japanese Investigative Sites Join International Trial of VS-6063 for Patients with Mesothelioma — Allowance by the PMDA Enables Verastem to Pursue Parallel Development in the Major Markets Worldwide – CAMBRIDGE, MA – May 12 — Verastem, Inc. (NASDAQ:VSTM), focused on discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells, today announced the expansion of its ongoing COMMAND study to include clinical trial sites in Japan. COMMAND is a registration-directed trial evaluating the Company’s lead candidate targeting cancer stem cells, VS-6063 (defactinib) a potent inhibitor of focal adhesion kinase (FAK), in patients with malignant pleural mesothelioma. Mesothelioma is a highly aggressive form of lung cancer and a high percentage of cases contain cancer stem cells. With the inclusion of Japan, COMMAND is now accruing patients and pursuing parallel clinical development in the major markets worldwide. “The incidence of mesothelioma, among the most aggressive and lethal cancers, is rapidly increasing in Japan and the survival rate for these patients is extremely poor,” said Professor Takashi Nakano, M.D., Ph.D., Chief Professor and Chairman, Department of Thoracic Oncology, Hyogo College of Medicine. ”New treatment options for patients with mesothelioma are urgently needed.” “Typically the Japanese development of novel oncology agents is delayed compared to the rest of the world,” said Professor Kazuhiko Nakagawa, M.D., Ph.D., Professor, Department of Medical Oncology, Kinki University Faculty of Medicine. “We were able to initiate and complete the Phase 1 assessment of VS-6063 in less than a year. By completing the trial so quickly, the ongoing COMMAND study can now include Japanese clinical sites in parallel with the other major countries participating in the trial.” Verastem recently reported the successful outcome of its Phase 1 trial of VS-6063 in Japanese patients with advanced solid tumors. The study results demonstrated that VS-6063 was well tolerated at all three dose levels tested. The data were consistent with the results from the US Phase 1 trial and there were no serious adverse events or evidence of dose-limiting toxicity. These results supported the Company’s application to the Japanese PMDA for the initiation of clinical trial sites to evaluate VS-6063 in Japanese patients with mesothelioma. “COMMAND is now open for patient enrollment at multiple sites in Japan,” said Dr. Joanna Horobin, Verastem Chief Medical Officer. “An important element of our overall global development strategy for VS-6063 is to pursue a path toward registration in Japan in parallel with our development efforts worldwide. We are committed to developing new treatments that can potentially make a meaningful difference in the lives of patients suffering with this deadly disease.” About Malignant Pleural Mesothelioma Malignant pleural mesothelioma is an aggressive form of cancer that occurs in the mesothelium, the thin layer of tissue that covers the lungs. Mesothelioma is associated with exposure to asbestos in most cases. According to the World Health Organization, there are a total of 59,000 cases of mesothelioma worldwide each year. Most mesotheliomas begin as one or more nodules that progressively grow to form a solid coating of tumor surrounding the lung leading to eventual suffocation and death. A high percentage of mesotheliomas contain cancer stem cells which are generally resistant to the currently available treatment options for mesothelioma. About COMMAND COMMAND is a registration-directed, double-blind, placebo-controlled trial of VS-6063 with Progression Free Survival (PFS) and Overall Survival (OS) as the primary endpoints. VS-6063 targets cancer stem cells. Cancer stem cells are an underlying cause of tumor progression and recurrence. The design of COMMAND allows the opportunity to enrich for patients with tumors low in the biomarker, merlin. Preclinical and early clinical research has demonstrated that low merlin levels may be predictive of increased effectiveness of FAK inhibitors such as VS-6063. The COMMAND study stratifies patients to evaluate the effect of VS-6063 in both the overall patient population and the subgroup of patients whose tumors are low in merlin. COMMAND is expected to enroll approximately 350-400 patients at clinical sites in 12 countries, including the US, UK, Japan, Australia, Canada, South Africa, New Zealand and countries in mainland Europe. Eligible patients who had a partial response or stable disease following standard first-line therapy with platinum/pemetrexed will be stratified to merlin low or high and then randomized to receive either placebo or 400 mg of defactinib. For more information visit www.COMMANDmeso.com About VS-6063 VS-6063 (defactinib) is an orally available compound designed to target cancer stem cells through the potent inhibition of focal adhesion kinase (FAK). Cancer stem cells are an underlying cause of tumor resistance to chemotherapy, recurrence and ultimate disease progression. Research by Robert Weinberg, Ph.D., scientific cofounder and chair of Verastem’s Scientific Advisory Board, and Verastem has demonstrated that the FAK pathway is critical for the growth and survival of cancer stem cells. VS-6063 is currently being studied in the registration-directed COMMAND trial in mesothelioma (www.COMMANDmeso.com), a Phase 1/1b study in combination with paclitaxel for patients with ovarian cancer and a Phase 2 trial in patients with KRas-mutated non-small cell lung cancer. VS-6063 has been granted orphan drug designation in the U.S. and E.U. for use in mesothelioma. About Verastem, Inc. Verastem, Inc. (NASDAQ: VSTM) is discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells. Cancer stem cells are an underlying cause of tumor recurrence and metastasis. Verastem is developing small molecule inhibitors of signaling pathways that are critical to cancer stem cell survival and proliferation: FAK, PI3K/mTOR and Wnt. For more information, please visit www.verastem.com. Forward-looking statements: This press release includes forward-looking statements about the Company’s strategy, future plans and prospects, including statements regarding the development of the Company’s compounds, including VS-6063, or defactinib, and the Company’s FAK inhibition program, the timeline for clinical development and regulatory approval of the Company’s compounds, the expected timing for the reporting of data from ongoing trials, and the structure of the Company’s planned or pending clinical trials, and potential indications for clinical development. The words “anticipate,” “appear,” “believe,” “estimate,” “expect,” “intend,” “may,” “plan,” “predict,” “project,” “target,” “potential,” “will,” “would,” “could,” “should,” “continue,” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Each forward-looking statement is subject to risks and uncertainties that could cause actual results to differ materially from those expressed or implied in such statement. Applicable risks and uncertainties include the risks that the preclinical testing of the Company’s compounds and preliminary data from clinical trials may not be predictive of the results or success of ongoing or later clinical trials, that data may not be available when we expect it to be, that enrollment of clinical trials may take longer than expected, that the Company will be unable to successfully complete the clinical development of its compounds, including VS-6063, that the development of the Company’s compounds will take longer or cost more than planned, and that the Company’s compounds will not receive regulatory approval or become commercially successful products. Other risks and uncertainties include those identified under the heading “Risk Factors” in the Company’s Annual Report on Form 10-K for the year ended December 31, 2013 and in any subsequent SEC filings. The forward-looking statements contained in this presentation reflect the Company’s current views with respect to future events, and the Company does not undertake and specifically disclaims any obligation to update any forward-looking statements. Verastem, Inc. Brian Sullivan (USA), 617-252-9314 bsullivan@verastem.com or Ambrose Lau (Japan), +81-3-5561-2915 verastemcommand@cosmopr.co.jp

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Mesothelioma Lawyer Week to Increase Awareness of Asbestos

New York Mesothelioma Lawyer Lauds Week Designated to Increase Awareness of Asbestos Sen. Baucus’ advocacy for asbestos victims merits special praise, says attorney Joseph W. Belluck of the New York personal injury firm of Belluck & Fox, LLP. New York, NY – March 24, 2012 – New York mesothelioma lawyer Joseph W. Belluck applauded the U.S. Senate – especially Sen. Max Baucus – for passing a resolution that designates the first week of April as “National Asbestos Awareness Week.” “The serious harm caused by exposure to asbestos is a nationwide and worldwide problem,” said Belluck, a partner in Belluck & Fox, LLP, a New York personal injury firm that is nationally recognized for its representation of mesothelioma victims. “Designating a national awareness week helps focus renewed attention on victims of asbestos disease,” Belluck said. “It also reminds us that more needs to be done to prevent harmful exposure to asbestos.” By unanimous consent, the Senate on March 6 passed a resolution designating the first week of April as “National Asbestos Awareness Week.” The Senate also urged the U.S. Surgeon General to educate people about health risk posed by asbestos. It’s the sixth year in a row that Sen. Baucus (D-Montana) has introduced the resolution. It honors the nearly 300 people in Libby, Montana, who have died of asbestos-related diseases such as mesothelioma. Mesothelioma is a cancer of the lining of the lungs and abdomen. It is associated with occupations that expose workers and veterans to breathing microscopic asbestos fibers. Many of the victims in Libby worked at the W.R. Grace Company vermiculite mine that closed in 1990. Baucus helped to get the U.S. Environmental Protection Agency to declare a public health emergency in Libby, Montana. “We’d like to single out for praise the determined efforts of Sen. Baucus, who has been actively involved in sponsoring asbestos awareness week resolutions year after year,” Belluck said. “Sen. Baucus knows firsthand the devastation that asbestos disease can cause in a small community.” Thousands of people throughout the United States face asbestos exposure each year. “As Sen. Baucus said, it’s important to keep making the public aware of the tragic impact of asbestos exposure,” Belluck said. “Public recognition of a problem is a positive step toward addressing it.” The New York law firm of Belluck & Fox is dedicated to securing compensation for victims of asbestos-related disease. The firm files personal injury lawsuits and wrongful death claims. It also works to increase public awareness of the dangers of asbestos. Approximately, 2,500 people in the U.S. are diagnosed each year with mesothelioma, according to the U.S. Centers for Disease Control and Prevention. The incurable cancer could be largely preventable if asbestos were banned, Belluck said. The U.S. has significantly decreased its consumption of asbestos but imports of the mineral fiber still continue for use in products such as roof materials. About Belluck & Fox, LLP Belluck & Fox, LLP, is a nationally recognized law firm that represents individuals with asbestos and mesothelioma claims, as well as victims of crime, motorcycle crashes, lead paint and other serious injuries. The firm provides personalized and professional representation and has won over $400 million in compensation for clients and their families. Partner Joseph W. Belluck is AV-rated by Martindale-Hubbell and is listed in Best Lawyers in America, New York Magazine’s “Best Lawyers in the New York Area” and in Super Lawyers. Mr. Belluck has won numerous cases involving injuries from asbestos, defective medical products, tobacco and lead paint, including a recent asbestos case that settled for more than $12 million. Partner Jordan Fox is a well-known asbestos and mesothelioma attorney who has been named to the Best Lawyers in America, New York Magazine’s “Best Lawyers in the New York Area” and to Super Lawyers. On two separate occasions his verdicts were featured as the National Law Journal’s Largest Verdict of the Year. He recently secured verdicts of $32 million and more than $19 million on behalf of individuals who had contracted mesothelioma from asbestos exposure. In September, Belluck & Fox, LLP, won a coveted spot on a list of America’s best law firms, which was published jointly by U.S. News & World Report and Best Lawyers magazine. The listing showcased 8,782 different law firms ranked in one or more of 81 major practice areas.




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Exposure to Asbestos Products Caused Lung Cancer

Exposure to Asbestos Products Caused Lung Cancer, Former Laborer Says Charleston – A couple from Salyersville (KY) is suing forty nine defendant corporations that are allegedly responsible for an asbestos-related lung cancer diagnosis. Will Press Conley and his wife Dorothy Conley have filed a suit in Kanawha Circuit Court on February 29. The suit says Mr. Conley was diagnosed with asbestos-related lung cancer in 2011 March. According to the complaint, the defendant companies exposed Conley to asbestos and products containing asbestos when working as a laborer for around 50 years from 1944. Despite being aware of the hazards of their asbestos products, the defendant companies failed to warn its workers and provide them with a safe working environment, the complaint says. The plaintiffs are asking for a jury trial.




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Woman’s Family Sues Killer Asbestos Companies

ST. LOUIS – The family of a deceased woman is suing 44 companies in a lawsuit filed in St. Louis Circuit Court, claiming that she was diagnosed with lung cancer because of her exposure to asbestos during her employment as a laborer with Bussmann Manufacturing Company for more than 10 years. According to the suit, Rodessa Norful worked with Bussmann from 1969 to 1980. The complaint doesn’t say where she was residing at. According to the plaintiffs, the companies exposed Norful to various products containing asbestos regularly during her job. She developed lung cancer on account of her continuous exposure to the hazardous mineral, the plaintiffs allege. The companies were aware of the risks associated with exposure to asbestos fibers, but they didn’t warn Norful or her co-workers, according to the complaint. Norful family is seeking compensatory and punitive damages.



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Workplace Exposure To Asbestos

Mesothelioma Compensation Center Points To A Recent CDC Study As A Good Reason For People Who Had Workplace Exposure To Asbestos Decades Ago To Not Be Complacent This week the Mesothelioma Compensation Center is pointing to a recent CDC study on latency periods for mesothelioma in workers who were exposed to asbestos between the 1960 and 2000 as a very good reason why these types of people should get annual check-ups that include an x-ray exam. June 24, 2014 – The Mesothelioma Compensation Center says, “We get heartbreaking calls almost every week where a family has reached out to us about getting one of the nation’s top mesothelioma compensation attorneys. The calls usually begin with the family explaining that their loved one had been sick with what was believed to be pneumonia and then passed away. “The reason they call our hotline is because an autopsy confirmed the cause of death was mesothelioma, not pneumonia. After a few questions we discover the individual worked in a manufacturing or industrial workplace, and/or served in the US Navy decades ago, which is where the possible exposure to asbestos occurred. So why is the Mesothelioma Compensation Center so focused on mesothelioma latency periods, and individuals who had heavy exposure to asbestos in the workplace? According to the CDC in January of 2014, “Because of long latency periods (10-40 years), workers exposed to asbestos in the 1960s and 1970s are now manifesting asbestos-associated diseases. Indeed, the mortality of asbestosis, and mesothelioma has increased from the 1960s to 2000. The National Institute of Occupational Safety and Health (NIOSH) data indicates that increased substantially from the 1960s to the 2000s; they are expected to continue occurring for decades.” http://www.atsdr.cdc.gov/csem/csem.asp?csem=29&po=7 “If we could impress on every person who served in the US Navy, and or worked in the manufacturing, industrial, construction, or automotive repair industries, and who had moderate to heavy exposure on the job we would say two things: Don’t be complacent. Get an annual chest x-ray that is focused on masses, or benign tumors in the lungs. “If the chest x-ray reveals a tumor or a mass, and a biopsy confirms it is mesothelioma, please call us immediately at 866-714-7466. Not only do we always provide instant access to the nation’s most skilled mesothelioma attorneys who will almost immediately travel to the diagnosed victim, we also do everything in our power to see to it the diagnosed victim and their family have almost immediate access to the nation’s top mesothelioma treatment specialists.” Information About Mesothelioma From The Mesothelioma Compensation Center For Diagnosed Victims And Their Families: High-risk groups for exposure to asbestos include: the US Navy Veterans, shipyard workers, oil refinery workers, manufacturing workers, plumbers, electricians, auto mechanics, machinists, or construction workers. Typically the exposure to asbestos occurred in the 1950s, 1960s, 1970s, or 1980s. US Navy Veterans account for a significant portion of all diagnosed victims of mesothelioma each year. According to the US Centers for Disease Control the average age for a diagnosed victim of mesothelioma is 72 years old. Each year between 2,500 and 3,000 US citizens will be diagnosed with mesothelioma. Mesothelioma is attributable to exposure to asbestos. According to the CDC the states with the highest incidence of mesothelioma include: Pennsylvania, Maine, New Jersey, West Virginia, Florida, Wyoming, and Washington. However, based on the calls the Mesothelioma Compensation Center receives diagnosed victims could be in any state including: California, New York, Texas, Massachusetts, Maryland, Virginia, North Carolina, Georgia, Louisiana, Oklahoma, Missouri, Ohio, Michigan, Iowa, Indiana, Illinois, Wisconsin, Minnesota, North Dakota, Montana, Nebraska, Kansas, Colorado, Utah, New Mexico, Arizona, Nevada, Idaho, Oregon, Hawaii, or Alaska. The Mesothelioma Compensation Center says, “If you call us at 866-714-6466, we will see to it that you have on the spot access to the nation’s most skilled mesothelioma attorneys, because these incredibly skilled legal experts consistently get the best financial compensation results for their clients on a nationwide basis.” For more information about a rare form of cancer caused by exposure to asbestos called mesothelioma, please visit the US Centers For Disease Control’s website: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5815a3.htm Contact Information M Thomas Martin Americas Watchdog 5 http://MesotheliomaCompensationCenter.com +1 (866) 714-6466


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Young Workers Face Greater Asbestos Cancer Risk

Mesothelioma Law Firm Warns Younger Workers More At Risk of Asbestos Cancer Young workers and those new to working in occupations where they are likely to encounter asbestos containing materials need extra protection as they may not be aware of how dangerous exposure to asbestos can be. This is even more so with asbestos hazards, as the fatal consequences caused by exposure to asbestos are not seen until decades later due to a long latency period between initial exposure and development of disease. March 16, 2012 – According to a recent report published in the European Respiratory Journal, Temporal Patterns of Occupational Asbestos Exposure and Risk of Pleural Mesothelioma, men under the age of 20 who are occupationally exposed to asbestos are more likely to later develop mesothelioma than are those exposed at later ages. These results highlight the fact that young workers and those new to the workplace, especially where asbestos exposure is known to be a risk, need extra protection. Young and inexperienced workers often lack the experience, knowledge and full understanding of how being exposed to asbestos products can lead to fatal illnesses such as mesothelioma. Exposure to asbestos causes mesothelioma (malignancy that develops in the lining of the lungs, heart, or abdomen that is often called asbestos cancer,) asbestosis (scarring of the lungs,) and other asbestos related cancers. Because the threat of asbestos is not obvious – fibers are microscopic and exposure doesn’t lead to immediate effects – young workers may lack the cognition to protect themselves from this occupational hazard. Clapper, Patti, Schweizer & Mason (CPSM), asbestos attorneys, have represented clients who died of mesothelioma as young as 35 years old – way too young! They urge employers and workers themselves to take precautions by: Identifying areas and products in the workplace that create risk of exposure to asbestos Attending trainings to learn what the hazards of asbestos are and how to avoid them Having a thorough understanding of the long term consequences of occupational exposure to asbestos Attending safety meetings and orientations that discuss the importance of and ways to avoid exposure. Following workplace protocols, including using personal protective equipment and clothing. CPSM Urges: Don’t Downplay the Danger of Asbestos Employers and more experienced, knowledgeable workers probably know about that asbestos presents a risk and that people of all ages, not just older workers, need to worry about protecting themselves to avoid later developing asbestos related diseases. The Occupational Safety and Hazard Administration has regulations for employers as well as guidelines for workers to follow specific to asbestos substances. If you or a loved one has been exposed to asbestos and developed mesothelioma, contact one of our asbestos attorneys today at 1-800-440-4262 for a free case evaluation. We have been standing up for and fighting for the rights of asbestos victims for over 30 years.    It’s what we do, and we’re good at it. Contact us today. About Clapper Patti Schweizer & Mason CPSM is a mesothelioma law firm dedicated exclusively to fighting for the rights of asbestos victims. CPSM has filed, fought and won multi-million dollar mesothelioma lawsuits on behalf of their clients, providing financial security for them and their families. After 30 years of experience, CPSM is considered top in the nation and experts in the field of asbestos law. In addition, they can provide recommendations for the best mesothelioma doctors and mesothelioma treatments for your individual case. Call today 1-800-440-4262. Sally Clapper Clapper, Patti, Schweizer & Mason 1-800-440-4262




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Asbestos Exposure Compensation

Mesothelioma Compensation Center Now Focuses On A NIOSH Study With The Emphasis Being Compensation For Manufacturing Workers Exposed To Asbestos Between 1969 And 2001 The Mesothelioma Compensation Center is calling attention to a recent National Institute for Occupational Safety and Health as wake up call for individuals who worked in the manufacturing sector between 1969 and 2000, because it indicates asbestos was present in what the Center considers to be a clean workplace. USA – June 19 – The Mesothelioma Compensation Center frequently gets phone calls from manufacturing workers who have no clue how, or where they could have been exposed to asbestos. This week the Center is pointing to a study from the National Institute for Occupational Safety and Health that indicates that between 1969 and 2000, manufacturing workers had a higher incidence of mesothelioma because of exposure to asbestos at the workplace. What the Compensation Center would like to explain to diagnosed victims and their family members who call them at 866-714-6466, is the compensation for these types of individuals can be worth over one million dollars provided they have the best possible mesothelioma attorneys. A January 2014 study from the National Institute for Occupational Safety and Health (NIOSH) examined records from a former IBM plant in Endicott, New York to assess whether occupational exposures at the plant put former workers at risk for job-related mortality and cancer. NIOSH conducted the study at the request of the NY State Department of Health (NYSDOH), Congressional representatives from New York, and community stakeholders. This study examined available records for 34,494 workers employed at the plant from 1969 to 2001. The study, now available online by the American Journal of Industrial Medicine, found that: Deaths from some types of cancer (rectal cancer, non-Hodgkin lymphoma, mesothelioma, pleural cancer) were more frequent in some groups of workers than would be expected from the general population. http://www.cdc.gov/niosh/updates/upd-01-06-14A.html The Mesothelioma Compensation Center says, “What we thought was amazing about this study was it focused in on manufacturing workers at an IBM manufacturing facility, and not the types of workplaces more commonly associated with asbestos exposure, and or mesothelioma. “Manufacturing or industrial workers who have been diagnosed with mesothelioma are strongly encouraged to call us anytime at 866-714-6466. We also encourage family members to contact the center so that we can instantly get them the contact information for one of the nation’s most qualified mesothelioma compensation attorneys. Please don’t settle for anything but the absolute best mesothelioma lawyer when considering a mesothelioma compensation claim. Choosing poorly can be an extremely costly mistake as we would like to explain.” Information About Mesothelioma From The Mesothelioma Compensation Center For Diagnosed Victims And Their Families: High-risk groups for exposure to asbestos include: the US Navy Veterans, shipyard workers, oil refinery workers, manufacturing workers, plumbers, electricians, auto mechanics, machinists, or construction workers. Typically the exposure to asbestos occurred in the 1950s, 1960s, 1970s, or 1980s. US Navy Veterans account for a significant portion of all diagnosed victims of mesothelioma each year. According to the US Centers for Disease Control the average age for a diagnosed victim of mesothelioma is 72 years old. Each year between 2,500 and 3,000 US citizens will be diagnosed with mesothelioma. Mesothelioma is attributable to exposure to asbestos. According to the CDC the states with the highest incidence of mesothelioma include: Pennsylvania, Maine, New Jersey, West Virginia, Florida, Wyoming, and Washington. However, based on the calls the Mesothelioma Compensation Center receives diagnosed victims could be in any state including: California, New York, Texas, Massachusetts, Maryland, Virginia, North Carolina, Georgia, Louisiana, Missouri, Ohio, Michigan, Iowa, Indiana, Illinois, Wisconsin, Minnesota, North Dakota, Montana, Nebraska, Kansas, Colorado, Utah, New Mexico, Arizona, Nevada, Idaho, Oregon, Hawaii, or Alaska. The Mesothelioma Compensation Center says, “If you call us at 866-714-6466, we will see to it that you have on the spot access to the nation’s most skilled mesothelioma attorneys, because these incredibly skilled legal experts consistently get the best financial compensation results for their clients on a nationwide basis.” *For more information about a rare form of cancer caused by exposure to asbestos called mesothelioma, please visit the US Centers For Disease Control’s website: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5815a3.htm Contact Information M Thomas Martin Americas Watchdog 5 http://MesotheliomaCompensationCenter.com +1 (866) 714-6466


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Cleaning Contractor Fined for Asbestos Violations

The Oregon DEQ (Department of Environmental Quality) has fined a cleaning company $5,035 for allegedly cleaning up asbestos from a Redmond duplex and improperly disposing the deadly material at a Bend landfill. The DEQ says Maricle Industries, which do business as ‘Service Master Cleaning Specialists’, doesn’t have license to handle asbestos abatement jobs. According to the DEQ, the company removed approximately 110 square feet of asbestos-contaminated ceiling tile while doing a fire cleanup at Redmond duplex, Elm Street, in 2011 October. Though the company is not authorized to do any sort of jobs involving asbestos handling, it disposed of the dangerous substance in the municipal waste area of the Knott Landfill, the DEQ says. Maricle Industries can appeal the fines until 22nd March.




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Boiler Maker Develops Malignant Asbestos Disease

A boiler maker claims he developed a number of health issues as a result of his occupation exposure to asbestos dust and fibers. Francis Champagne has filed a lawsuit against 25 companies for negligently exposing him to deadly asbestos fibers and therefore causing the malignant disease he developed. He had filed a separate lawsuit in the past over some non-malignant asbestos-related illnesses. His previous claims have been settled already. Champagne filed his complaint on 6th March in Jefferson County District Court. He says his diseases are linked to toxic fibers to which he was exposed while working with and around various asbestos products. The dates of his employment are not mentioned in the lawsuit. The defendant companies manufactured, distributed, or used asbestos products, but failed to warn employees regarding the hazards associated with them, the complaint says. Champagne is seeking exemplary damages.




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Study Says Disease Predicts Mesothelioma

European Study Says Disease Progression Predicts Mesothelioma Survival Better Than Treatment Response, According to Surviving Mesothelioma New research suggests that how quickly mesothelioma progresses after treatment may predict the likelihood of survival better than treatment response. Raleigh, NC – August 29 – Scientists from four European countries say they have independently validated the idea that progression-free survival correlates with overall survival of mesothelioma. Surviving Mesothelioma has just posted an article on the new research. Click here to read it now. Doctors from France, Belgium, UK and The Netherlands studied the cases of 523 mesothelioma patients who were part of 10 European chemotherapy studies. “PFSR-18 [progression-free survival at 18 weeks after treatment] was strongly correlated and discriminated patients with better overall survival from the poorer prognosis patients,” writes lead investigator Baktiar Hasan of the European Organisation for Research and Treatment of Cancer headquarters in Brussels, Belgium. The study, published in the European Journal of Cancer, found that a patient’s lack of mesothelioma progressionat 9 weeks after chemotherapy was also a predictor of expected survival. “The suggestion that treatment response may not necessarily be the best predictor of survival should be encouraging news for mesothelioma patients whose tumors have not been reduced in size by chemotherapy,” says Alex Strauss, Managing Editor of Surviving Mesothelioma. To read more results of this study and what it may mean for patients and families, see Mesothelioma Survival: Treatment Response May Not Be the Best Predictor, now available on the Surviving Mesothelioma website. Hasan, B et al, “Progression free survival rate at 9 and 18 weeks predict overall survival in patients with malignant pleural mesothelioma: An individual patients pooled analysis of 10 European Organisation for Research and Treatment of Cancer Lung Cancer Group studies and an independent study validation”, August 21, 2014, European Journal of Cancer Epub ahead of print, http://www.ncbi.nlm.nih.gov/pubmed/25155251. For nearly ten years, Surviving Mesothelioma has brought readers the most important and ground-breaking news on the causes, diagnosis and treatment of mesothelioma. All Surviving Mesothelioma news is gathered and reported directly from the peer-reviewed medical literature. Written for patients and their loved ones, Surviving Mesothelioma news helps families make more informed decisions. Contact Information Michael Ellis Cancer Monthy http://www.survivingmesothelioma.com +1 (919) 570-8595

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